This is not a complete list of side effects and others may occur. If you notice any other effects, check with your healthcare professional. Understand that finding an antidepressant that works well for depressive symptoms with minimal side effects is everyone’s ultimate goal. Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Physicians should routinely May make these conditions worse. Vortioxetine is extensively metabolized or broken down by the CYP2D6 liver enzymes. Most people aren’t aware of the factors that can influence the severity and number of side effects. In female patients, the overall It was usually Hyponatremia has been reported with the treatment Make sure you tell your doctor if you have any other medical problems, especially: Take this medicine only as directed by your doctor. This risk must be balanced with the clinical need. Learn how your comment data is processed. Commonly reported side effects of vortioxetine include: diarrhea, male sexual disorder, and nausea. Nausea was the most common adverse reaction reported as a reason for discontinuation. Portions of this document last updated: Oct. 01, 2020. A majority of side effects are subject to individual variation. drug cannot be directly compared to rates in the clinical studies of another occurred at a rate equal to or less than placebo. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locater Tool Including 24 Hour, Pharmacies. How long have you been taking Brintellix? Do not take vortioxetine if you have taken a monoamine oxidase (MAO) inhibitor (such as Eldepryl®, Marplan®, Nardil®, Parnate®), methylene blue, … Some side effects may not be reported. Subscribe to newsletters for the latest medication news, alerts, new drug approvals and more. Nausea was more common in females than males. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. BRINTELLIX 10 mg/day to 20 mg/day had nausea at the end of the 6 to 8 week Table 3: ASEX Incidence of Treatment Emergent Sexual patients treated with BRINTELLIX in 6 to 8 week placebo-controlled studies It is unknown if it would affect a fetus. See our safe care and visitor guidelines, plus trusted coronavirus information. Available for Android and iOS devices. It may take some experimentation to find the right medication that you can tolerate and that works for your depression. constipation and vomiting. A total of 2586 patients were exposed to at least one dose of TRINTELLIX in open-label studies, 1727 were exposed to TRINTELLIX for six months and 885 were exposed for at least one year. Even Primperan doesn’t help. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locater Tool Including 24 Hour, Pharmacies. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. BRINTELLIX or placebo in any fixed dose group. Hence, vortioxetine's anti-anxiety effects may be partially related to mood improvement in patients with both depression and anxiety. Follow your doctor's orders or the directions on the label. O 0, 3. Over the long-term, certain drugs can influence physiology and result in side effects after an extended term. Voluntarily Reported Adverse Reactions of Sexual Dysfunction. Call your doctor for medical advice about side effects. TRINTELLIX had no significant effect on body weight as measured by the mean change from baseline in the 6 to 8 week placebo-controlled studies. Check with your doctor first before taking any other medicines with vortioxetine. Learn to Spot Depression: Symptoms, Warning Signs, Medication, Nortriptyline Hydrochloride Oral Solution, * Incidence based on number of subjects with sexual dysfunction during the study/number of subjects without sexual dysfunction at baseline. considered mild or moderate in intensity and the median duration was 2 weeks. Usually the short-term side effects tend to lessen or completely subside after a few weeks. In other words, two people can take the same medication, at the exact same dose, for the exact same time period and have completely different reactions. These side effects may go away during treatment as your body adjusts to the medicine. Vortioxetine may cause a serious condition called serotonin syndrome if taken together with some medicines such as buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), lithium (Eskalith®, Lithobid®), tryptophan, St. John's wort, other medicines for depression (such as amitriptyline, nortriptyline), or some pain or migraine medicines (eg, rizatriptan, sumatriptan, tramadol, Frova®, Imitrex®, Maxalt®, Relpax®, Ultram®, Zomig®). Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. placebo-controlled studies. Previous post: Lortab Withdrawal Symptoms + How Long Will They Last? Vortioxetine may cause some teenagers and young adults to be agitated, irritable, or display other abnormal behaviors. I’m in my second week now and the itching is just getting more and more worse. placebo-controlled studies. Vortioxetine has not been evaluated for use in pediatric patients. that occurred in ≥ 2% of MDD patients treated with any BRINTELLIX dose and It is important that your doctor check your progress at regular visits to allow changes in your dose and help reduce any side effects. Call your doctor for medical advice about side effects. A single copy of these materials may be reprinted for noncommercial personal use only. and placebo-treated patients. Our Trintellix (vortioxetine) tablets Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. The following adverse reactions are discussed in greater Check with your doctor immediately if any of the following side effects occur while taking vortioxetine: Some side effects of vortioxetine may occur that usually do not need medical attention.